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Target
RNA-directed RNA polymerase
Ligand
BDBM50191527
Substrate
n/a
Meas. Tech.
ChEMBL_932863 (CHEMBL3074361)
IC50
66600000±n/a nM
Citation
  TBA Med Chem Res 22:1866-1883 (2013)    Article 
Target
Name:
RNA-directed RNA polymerase
Synonyms:
2.7.7.48 | NS5B | RNA-directed RNA polymerase
Type:
PROTEIN
Mol. Mass.:
13231.83
Organism:
Hepatitis C virus genotype 1
Description:
ChEMBL_106647
Residue:
121
Sequence:
RCFDSTVTENDIRVEESIYQCCDLDPQARVAIKSLTERLYVGGPFTNSRGENCGYRRCRASGVLTTRCGNTLTCYMKAQAACRAARLRDCTMLVSGDDLVVICESAGAQEDAASLRAFTEA
  
Inhibitor
Name:
BDBM50191527
Synonyms:
2-[4-(4'-chloro-4-dimethylcarbamoylbiphenyl-2-ylmethoxy)-phenyl]-1-cyclohexyl-1H-benzimidazole-5-carboxylic acid | CHEMBL376688
Type:
Small organic molecule
Emp. Form.:
C36H34ClN3O4
Mol. Mass.:
608.126
SMILES:
CN(C)C(=O)c1ccc(c(COc2ccc(cc2)-c2nc3cc(ccc3n2C2CCCCC2)C(O)=O)c1)-c1ccc(Cl)cc1
Structure:
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