Reaction Details Report a problem with these data
Target
Tissue factor
Ligand
BDBM50068224
Substrate
n/a
Meas. Tech.
ChEMBL_932090 (CHEMBL3072496)
IC50
0.960000±n/a nM
Citation
  TBA Med Chem Res 22:3242-3246 (2013)    Article 
Target
Name:
Tissue factor
Synonyms:
CD_antigen=CD142 | Coagulation factor III | Coagulation factor VII/tissue factor | F3 | TF | TF_HUMAN | Thromboplastin | Tissue factor
Type:
PROTEIN
Mol. Mass.:
33067.61
Organism:
Homo sapiens (Human)
Description:
ChEMBL_936735
Residue:
295
Sequence:
METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
  
Inhibitor
Name:
BDBM50068224
Synonyms:
(E)-1,3-Bis-(4-hydroxy-phenyl)-propenone | 1,3-bis(4-hydroxyphenyl)prop-2-en-1-one | 4',4-Dihydroxychalcone | 4,4'-dihydroxychalcone | CHEMBL145927
Type:
Small organic molecule
Emp. Form.:
C15H12O3
Mol. Mass.:
240.254
SMILES:
Oc1ccc(\C=C\C(=O)c2ccc(O)cc2)cc1
Structure:
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