Reaction Details Report a problem with these data
Target
Platelet-activating factor receptor
Ligand
BDBM50035264
Substrate
n/a
Meas. Tech.
ChEMBL_158194 (CHEMBL767884)
IC50
11800±n/a nM
Citation
 Sawyer, DA; Beams, RM; Blackwell, GJ; Brockwell, MA; Cheesman, NJ; Demaine, DA; Garland, LG; Hodson, HF; Hyde, RM; Islip, PJ Development of a novel series of trialkoxyaryl derivatives as specific and competitive antagonists of platelet activating factor. J Med Chem 38:2130-7 (1995) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50035264
Synonyms:
CHEMBL70229 | {2-[4-(4-Hexyloxy-3,5-dimethoxy-benzoyloxy)-phenyl]-ethyl}-trimethyl-ammonium; iodide
Type:
Small organic molecule
Emp. Form.:
C26H38NO5
Mol. Mass.:
444.5831
SMILES:
CCCCCCOc1c(OC)cc(cc1OC)C(=O)Oc1ccc(CC[N+](C)(C)C)cc1
Structure:
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