Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50491518
Substrate
n/a
Meas. Tech.
ChEMBL_959620 (CHEMBL2382690)
Ki
147±n/a nM
Citation
 Stössel, A; Schlenk, M; Hinz, S; Küppers, P; Heer, J; Gütschow, M; Müller, CE Dual targeting of adenosine A(2A) receptors and monoamine oxidase B by 4H-3,1-benzothiazin-4-ones. J Med Chem 56:4580-96 (2013) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50491518
Synonyms:
CHEMBL2382420
Type:
Small organic molecule
Emp. Form.:
C19H18N2O2S
Mol. Mass.:
338.423
SMILES:
Cc1ccc2nc(NC(=O)CCCc3ccccc3)sc(=O)c2c1
Structure:
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