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Target
D(1A) dopamine receptor
Ligand
BDBM50038351
Substrate
n/a
Meas. Tech.
ChEMBL_61342 (CHEMBL879549)
Ki
>3000±n/a nM
Citation
 Minor, DL; Wyrick, SD; Charifson, PS; Watts, VJ; Nichols, DE; Mailman, RB Synthesis and molecular modeling of 1-phenyl-1,2,3,4-tetrahydroisoquinolines and related 5,6,8,9-tetrahydro-13bH-dibenzo[a,h]quinolizines as D1 dopamine antagonists. J Med Chem 37:4317-28 (1995) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50038351
Synonyms:
10-Bromo-6-methyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridin-11-ol | CHEMBL336218
Type:
Small organic molecule
Emp. Form.:
C18H18BrNO
Mol. Mass.:
344.246
SMILES:
CN1Cc2ccccc2C2C1CCc1cc(Br)c(O)cc21
Structure:
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