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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50007410
Substrate
n/a
Meas. Tech.
ChEMBL_1280662 (CHEMBL3097103)
Ki
0.120000±n/a nM
Citation
 Motel, WC; Healy, JR; Viard, E; Pouw, B; Martin, K; Matsumoto, RR; Coop, A Chlorophenylpiperazine analogues as high affinity dopamine transporter ligands. Bioorg Med Chem Lett 23:6920-6922 (2013) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50007410
Synonyms:
1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine | CHEMBL112125
Type:
Small organic molecule
Emp. Form.:
C19H23ClN2
Mol. Mass.:
314.852
SMILES:
Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1
Structure:
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