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Target
Delta-type opioid receptor
Ligand
BDBM50494875
Substrate
n/a
Meas. Tech.
ChEMBL_1280730 (CHEMBL3097539)
Ki
1.1±n/a nM
Citation
 Nemoto, T; Ida, Y; Iihara, Y; Nakajima, R; Hirayama, S; Iwai, T; Fujii, H; Nagase, H The most effective influence of 17-(3-ethoxypropyl) substituent on the binding affinity and the agonistic activity in KNT-127 derivatives, ? opioid receptor agonists. Bioorg Med Chem 21:7628-47 (2013) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50494875
Synonyms:
CHEMBL4296727
Type:
Small organic molecule
Emp. Form.:
C25H26Cl2F2N2O2
Mol. Mass.:
495.389
SMILES:
Cl.Cl.[H][C@]12Cc3ccc(O)cc3[C@@]3(CCN1CC(F)F)Cc1nc4ccccc4cc1C[C@@]23O |r,TLB:6:5:32:15.14.13,THB:10:11:32:15.14.13|
Structure:
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