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Target
Mu-type opioid receptor
Ligand
BDBM50494880
Substrate
n/a
Meas. Tech.
ChEMBL_1280731 (CHEMBL3097540)
Ki
47±n/a nM
Citation
 Nemoto, T; Ida, Y; Iihara, Y; Nakajima, R; Hirayama, S; Iwai, T; Fujii, H; Nagase, H The most effective influence of 17-(3-ethoxypropyl) substituent on the binding affinity and the agonistic activity in KNT-127 derivatives, ? opioid receptor agonists. Bioorg Med Chem 21:7628-47 (2013) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44431.62
Organism:
MOUSE
Description:
OPIATE Mu OPRM1 MOUSE::P42866
Residue:
398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50494880
Synonyms:
CHEMBL4296736
Type:
Small organic molecule
Emp. Form.:
C27H32Cl2N2O3
Mol. Mass.:
503.461
SMILES:
Cl.Cl.[H][C@]12Cc3ccc(O)cc3[C@@]3(CCN1CCOCC)Cc1nc4ccccc4cc1C[C@@]23O |r,TLB:6:5:33:15.14.13,THB:10:11:33:15.14.13|
Structure:
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