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Target
Vitamin D3 receptor A
Ligand
BDBM50496699
Substrate
n/a
Meas. Tech.
ChEMBL_1330621 (CHEMBL3222526)
EC50
1.2±n/a nM
Citation
 Huet, T; Maehr, H; Lee, HJ; Uskokovic, MR; Suh, N; Moras, D; Rochel, N Structure-function study of gemini derivatives with two different side chains at C-20, Gemini-0072 and Gemini-0097. Medchemcomm 2:424-429 (2011) [PubMed]  Article 
Target
Name:
Vitamin D3 receptor A
Synonyms:
1,25-dihydroxyvitamin D3 receptor A | Nuclear receptor subfamily 1 group I member 1-A | VDR-A | VDRA_DANRE | Vitamin D3 receptor A | nr1i1a | vdr | vdra
Type:
PROTEIN
Mol. Mass.:
50869.54
Organism:
Danio rerio
Description:
ChEMBL_108257
Residue:
453
Sequence:
MLTENSAVNSGGKSKCEAGACESRVNGDATSVMDLMAVSTSATGQDEFDRNAPRICGVCGDKATGFHFNAMTCEGCKGFFRRSMKRKASFTCPFNGNCTITKDNRRHCQACRLKRCIDIGMMKEFILTDEEVQRKKDLIMKRKEEEAAREARKPRLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVREGPVTRSASRAASLHSLSDASSDSFNHSPESVDTKLNFSNLLMMYQDSGSPDSSEEDQQSRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEVS
  
Inhibitor
Name:
BDBM50496699
Synonyms:
CHEMBL3220716
Type:
Small organic molecule
Emp. Form.:
C32H54O4
Mol. Mass.:
502.7688
SMILES:
[H][C@@]1(CC[C@@]2([H])\C(CCC[C@]12C)=C\C=C1\C[C@H](O)C[C@@H](O)C1=C)C(CCCC(C)(C)O)CCCC(C)(C)O |r|
Structure:
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