Reaction Details
Report a problem with these data
Report a problem with these dataTarget
B2 bradykinin receptor
Ligand
BDBM50045214
Substrate
n/a
Meas. Tech.
ChEBML_40275
Ki
3030±n/a nM
Citation
Chakravarty, S; Wilkins, D; Kyle, DJ Design of potent, cyclic peptide bradykinin receptor antagonists from conformationally constrained linear peptides. J Med Chem 36:2569-71 (1993) [PubMed] Article More Info.:
Target
Name:
B2 bradykinin receptor
Synonyms:
B2 bradykinin receptor | B2R | BDKRB2 | BK-2 receptor | BKRB2_CAVPO | Bradykinin B2 receptor
Type:
n/a
Mol. Mass.:
42217.03
Organism:
Cavia porcellus
Description:
n/a
Residue:
372
Sequence:
MFNITSQVSALNATLAQGNSCLDAEWWSWLNTIQAPFLWVLFVLAVLENIFVLSVFFLHKSSCTVAEIYLGNLAVADLILAFGLPFWAITIANNFDWLFGEVLCRMVNTMIQMNMYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCALLLSSPMLVFRTMKDYRDEGHNVTACLIIYPSLTWQVFTNVLLNLVGFLLPLSIITFCTVQIMQVLRNNEMQKFKEIQTERRATVLVLAVLLLFVVCWLPFQIGTFLDTLRLLGFLPGCWEHVIDLITQISSYLAYSNSCLNPLVYVIVGKRFRKKSREVYHGLCRSGGCVSEPAQSENSMGTLRTSISVDRQIHKLQDWARSSSEGTPPGLL
Inhibitor
Name:
BDBM50045214
Synonyms:
CHEMBL2370035 | D-Arg-Arg-Pro-Hyp-Gly-N-methylPhe-Ser-D-Tic-Oic-Arg
Type:
Small organic molecule
Emp. Form.:
C63H95N19O13
Mol. Mass.:
1326.5479
SMILES:
[#6]-[#6](-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H](-[#8])-[#6]-[#7]-1-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7][C@@]([#6])([#6]-c1ccccc1)[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-1-[#6]-c2ccccc2-[#6]-[#6@@H]-1-[#6](=O)-[#7]-1-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](-[#8])=O
Structure:
