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Target
Beta-galactosidase
Ligand
BDBM50261423
Substrate
n/a
Meas. Tech.
ChEMBL_1438445 (CHEMBL3384257)
Ki
16±n/a nM
Citation
 Fan, QH; Claunch, KA; Striegler, S Structure-activity relationship of highly potent galactonoamidine inhibitors toward ?-galactosidase (Aspergillus oryzae). J Med Chem 57:8999-9009 (2014) [PubMed]  Article 
Target
Name:
Beta-galactosidase
Synonyms:
3.2.1.23 | Beta-galactosidase
Type:
PROTEIN
Mol. Mass.:
100763.98
Organism:
Aspergillus oryzae
Description:
ChEMBL_109122
Residue:
909
Sequence:
MASLMKVYKLWVDIIAQNPANRHELTSQQRHVFSAEDPEKPLQDIVTWDEYSILVRGERILFFSGEFHPFRLPSPGLWLDVFQKIRALGYSGVSFYLMWGLLEGEPGHVRTEGVFALDGFFNAASQAGIYLLARPGPYINAEVSGGGFPSWVQRIEGSVRTTDPTFLNATKNYISTIGEIISKVQITNGGPVILFQLENEYSICEGAPSHEELNFCLEKDYMAAIEQQFRDAEIVVPFVNNDAVALGDWAPGTGQGAIDIYGFDNYPFGWGNGYASPENWTQITDPLTQYNFSQHQSMSPGTPFSIIEFQGGAPDPWGGTGADVCAEMVSNIFARVFYKINYDFRITIFNLYMMLGGTNWGNLGYSSGYTSYDVGAAIIEDRQITREKYSEIKLEAQFLQVSPAYITSKPHSPCSGCYTNASALMTTRLQGESTNFYIIRHSNYIVTQSTSYEWRANTSQGSITVPQPGGSSTLHGRDSKFHVTDCDLGGINLIYPTAETFTWRRHGSKSVLVLYGGEDEIHEFAVDSNLGNATTIEGSNVRLGKRGATFVVQWDHLDVYLLWRNEAYQYWVMDLPAPEPLDLHASPSRTNSSVIVKAGYLLRNASISENTLHLTGDVNATSTVELISAPPGCCSDVLYDGNRLQNISNTNGRVSGVVPYIDPKLAIPEMESLEWRYLDSLPEGEEKSLYLSTQGGYAYGHSVWLDSTYLGSWQGNPAIQNYNQTLQFPQSLQGDEHYVLTILIDNLGLDLNFELNTNTMKSPRGLLDYDLSGHNSWKITGNLGGEQYREHSRGPLNKGSTFVERQGYHLSGALNSTKAEWQTRTPQEGLSAAGVGLFATTFSLDYPQGYDIPTSVYVTIPTTHQSIVNNTGPQTEYPIPEGILNHHGGNHLAHHLLGSGRKWGKAGRD
  
Inhibitor
Name:
BDBM50261423
Synonyms:
CHEMBL3359123
Type:
Small organic molecule
Emp. Form.:
C14H17F3N2O4
Mol. Mass.:
334.291
SMILES:
OC[C@H]1N\C(=N/Cc2ccc(cc2)C(F)(F)F)[C@H](O)[C@@H](O)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: