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Target
Kappa-type opioid receptor
Ligand
BDBM50045792
Substrate
n/a
Meas. Tech.
ChEBML_220942
Ki
21±n/a nM
Citation
 Mitch, CH; Leander, JD; Mendelsohn, LG; Shaw, WN; Wong, DT; Cantrell, BE; Johnson, BG; Reel, JK; Snoddy, JD; Takemori, AE 3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: opioid antagonists with potent anorectant activity. J Med Chem 36:2842-50 (1993) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42744.99
Organism:
Cavia porcellus (domestic guinea pig)
Description:
P41144
Residue:
380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
  
Inhibitor
Name:
BDBM50045792
Synonyms:
3-[3,4-Dimethyl-1-(4-methyl-pent-4-enyl)-piperidin-4-yl]-phenol | CHEMBL96022
Type:
Small organic molecule
Emp. Form.:
C19H29NO
Mol. Mass.:
287.4397
SMILES:
C[C@H]1CN(CCCC(C)=C)CC[C@@]1(C)c1cccc(O)c1
Structure:
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