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Target
Thromboxane A2 receptor
Ligand
BDBM50047302
Substrate
n/a
Meas. Tech.
ChEBML_212937
Kd
11±n/a nM
Citation
 Misra, RN; Brown, BR; Sher, PM; Patel, MM; Hall, SE; Han, WC; Barrish, JC; Kocy, O; Harris, DN; Goldenberg, HJ Interphenylene 7-oxabicyclo[2.2.1]heptane oxazoles. Highly potent, selective, and long-acting thromboxane A2 receptor antagonists. J Med Chem 36:1401-17 (1993) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50047302
Synonyms:
3-(2-{3-[4-(4-Cyclohexyl-butylthiocarbamoyl)-oxazol-2-yl]-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl}-phenyl)-propionic acid | CHEMBL416395
Type:
Small organic molecule
Emp. Form.:
C30H40N2O4S
Mol. Mass.:
524.715
SMILES:
OC(=O)CCc1ccccc1CC1C2CCC(O2)C1c1nc(co1)C(=S)NCCCCC1CCCCC1 |TLB:11:12:17:15.14,THB:19:18:17:15.14|
Structure:
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