Reaction Details Report a problem with these data
Target
Sodium- and chloride-dependent creatine transporter 1
Ligand
BDBM50048110
Substrate
n/a
Meas. Tech.
ChEMBL_217034 (CHEMBL821568)
Ki
130000±n/a nM
Citation
 Patel, PJ; Messer, WS; Hudson, RA Inhibition and inactivation of presynaptic cholinergic markers using redox-reactive choline analogs. J Med Chem 36:1893-901 (1993) [PubMed]  Article 
Target
Name:
Sodium- and chloride-dependent creatine transporter 1
Synonyms:
CHOT1 | CT1 | Creatine transporter | Creatine transporter 1 | SC6A8_RAT | Slc6a8 | Sodium- and chloride-dependent creatine transporter 1 | Solute carrier family 6 member 8
Type:
PROTEIN
Mol. Mass.:
70632.63
Organism:
Rattus norvegicus
Description:
ChEMBL_49276
Residue:
635
Sequence:
MAKKSAENGIYSVSGDEKKGPLIVSGPDGAPSKGDGPAGLGAPSSRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSTGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVVYYKPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPIWGLHHLEYRAQDADVRGLTTLTPVSESSKVVVVESVM
  
Inhibitor
Name:
BDBM50048110
Synonyms:
CHEMBL57055 | [2-(3,4-Dihydroxy-phenyl)-2-hydroxy-ethyl]-trimethyl-ammonium; iodide
Type:
Small organic molecule
Emp. Form.:
C11H18NO3
Mol. Mass.:
212.265
SMILES:
C[N+](C)(C)CC(O)c1ccc(O)c(O)c1
Structure:
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