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Target
G-protein coupled receptor 55
Ligand
BDBM50500391
Substrate
n/a
Meas. Tech.
ChEMBL_1546174 (CHEMBL3749317)
EC50
12±n/a nM
Citation
 Yrjölä, S; Parkkari, T; Navia-Paldanius, D; Laitinen, T; Kaczor, AA; Kokkola, T; Adusei-Mensah, F; Savinainen, JR; Laitinen, JT; Poso, A; Alexander, A; Penman, J; Stott, L; Anskat, M; Irving, AJ; Nevalainen, TJ Potent and selective N-(4-sulfamoylphenyl)thiourea-based GPR55 agonists. Eur J Med Chem 107:119-32 (2016) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 55
Synonyms:
G protein-coupled receptor 55 | GPR55 | GPR55_HUMAN
Type:
PROTEIN
Mol. Mass.:
36649.72
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1292265
Residue:
319
Sequence:
MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
  
Inhibitor
Name:
BDBM50500391
Synonyms:
CHEMBL3747626
Type:
Small organic molecule
Emp. Form.:
C28H25N3O3S2
Mol. Mass.:
515.646
SMILES:
Cc1ccc(CNS(=O)(=O)c2ccc(NC(=S)NC(=O)c3ccc(cc3)-c3ccccc3)cc2)cc1
Structure:
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