Reaction Details Report a problem with these data
Target
Carbonic anhydrase 7
Ligand
BDBM50500679
Substrate
n/a
Meas. Tech.
ChEMBL_1549337 (CHEMBL3755043)
Ki
0.270000±n/a nM
Citation
 Villalba, ML; Palestro, P; Ceruso, M; Gonzalez Funes, JL; Talevi, A; Bruno Blanch, L; Supuran, CT; Gavernet, L Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action. Bioorg Med Chem 24:894-901 (2016) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50500679
Synonyms:
CHEMBL3752852
Type:
Small organic molecule
Emp. Form.:
C8H18N2O4S
Mol. Mass.:
238.305
SMILES:
COC(=O)CCNS(=O)(=O)NCC(C)C
Structure:
Search PDB for entries with ligand similarity: