Reaction Details Report a problem with these data
Target
Retinoic acid receptor beta
Ligand
BDBM31885
Substrate
n/a
Meas. Tech.
ChEMBL_195489 (CHEMBL798911)
Kd
679±n/a nM
Citation
 Yu, KL; Spinazze, P; Ostrowski, J; Currier, SJ; Pack, EJ; Hammer, L; Roalsvig, T; Honeyman, JA; Tortolani, DR; Reczek, PR; Mansuri, MM; Starrett, JE Retinoic acid receptor beta,gamma-selective ligands: synthesis and biological activity of 6-substituted 2-naphthoic acid retinoids. J Med Chem 39:2411-21 (1996) [PubMed]  Article 
Target
Name:
Retinoic acid receptor beta
Synonyms:
HAP | HBV-activated protein | NR1B2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RAR-epsilon | RARB | RARB_HUMAN | Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta | Retinoic acid receptor beta | Retinoid receptor
Type:
PROTEIN
Mol. Mass.:
50498.70
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1458015
Residue:
455
Sequence:
MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPATIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ
  
Inhibitor
Name:
BDBM31885
Synonyms:
BMS184394 | CHEMBL82089
Type:
Small organic molecule
Emp. Form.:
C26H28O3
Mol. Mass.:
388.4987
SMILES:
CC1(C)CCC(C)(C)c2cc(ccc12)C(O)c1ccc2cc(ccc2c1)C(O)=O
Structure:
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