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Target
Vasopressin V2 receptor
Ligand
BDBM50052923
Substrate
n/a
Meas. Tech.
ChEMBL_215007 (CHEMBL818806)
IC50
4100±n/a nM
Citation
 Ogawa, H; Yamashita, H; Kondo, K; Yamamura, Y; Miyamoto, H; Kan, K; Kitano, K; Tanaka, M; Nakaya, K; Nakamura, S; Mori, T; Tominaga, M; Yabuuchi, Y Orally active, nonpeptide vasopressin V2 receptor antagonists: a novel series of 1-[4-(benzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepines and related compounds. J Med Chem 39:3547-55 (1996) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
AVPR V2 | Antidiuretic hormone receptor | Avpr2 | Renal-type arginine vasopressin receptor | V2R_RAT | VASOPRESSIN V2 | Vasopressin receptor
Type:
G-protein coupled receptor
Mol. Mass.:
40761.85
Organism:
Rattus norvegicus (Rat)
Description:
n/a
Residue:
371
Sequence:
MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLGALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGPSERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEAPLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCATASSSLMKDTPS
  
Inhibitor
Name:
BDBM50052923
Synonyms:
CHEMBL116820 | N-[4-(2,3-Dihydro-benzo[1,4]oxazine-4-carbonyl)-phenyl]-2-methyl-benzamide
Type:
Small organic molecule
Emp. Form.:
C23H20N2O3
Mol. Mass.:
372.4165
SMILES:
Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCOc2ccccc12
Structure:
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