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Target
Retinoic acid receptor beta
Ligand
BDBM50052961
Substrate
n/a
Meas. Tech.
ChEMBL_195642 (CHEMBL795960)
Kd
4239.0±n/a nM
Citation
 Beard, RL; Colon, DF; Song, TK; Davies, PJ; Kochhar, DM; Chandraratna, RA Synthesis and structure-activity relationships of retinoid X receptor selective diaryl sulfide analogs of retinoic acid. J Med Chem 39:3556-63 (1996) [PubMed]  Article 
Target
Name:
Retinoic acid receptor beta
Synonyms:
Nr1b2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RARB_MOUSE | Rarb
Type:
PROTEIN
Mol. Mass.:
53344.93
Organism:
Mus musculus
Description:
ChEMBL_195641
Residue:
482
Sequence:
MSTSSHACPVPAVRGHMTHYPAAPYPLLFPPVIRGLSLPPLHGLHGHPPPSGCSTPSPASVGQACQRTTGGSQFAASTKWTPSLNAAIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNIAEHSPSVSPSSVENSGVSQSPLLQ
  
Inhibitor
Name:
BDBM50052961
Synonyms:
4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-ylsulfanyl)-benzoic acid | CHEMBL119781
Type:
Small organic molecule
Emp. Form.:
C21H24O2S
Mol. Mass.:
340.479
SMILES:
CC1(C)CCC(C)(C)c2cc(Sc3ccc(cc3)C(O)=O)ccc12
Structure:
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