Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50053937
Substrate
n/a
Meas. Tech.
ChEMBL_29459 (CHEMBL642188)
Ki
7.55±n/a nM
Citation
 Poulsen, SA; Quinn, RJ Synthesis and structure-activity relationship of pyrazolo[3,4-d]pyrimidines: potent and selective adenosine A1 receptor antagonists. J Med Chem 39:4156-61 (1996) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50053937
Synonyms:
2-(4-Methylsulfanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-pentanoic acid amide | CHEMBL338723
Type:
Small organic molecule
Emp. Form.:
C17H19N5OS2
Mol. Mass.:
373.496
SMILES:
CCCC(Sc1nc(SC)c2cnn(-c3ccccc3)c2n1)C(N)=O
Structure:
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