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Target
D(2) dopamine receptor
Ligand
BDBM50054381
Substrate
n/a
Meas. Tech.
ChEMBL_62555 (CHEMBL674067)
Ki
>1000±n/a nM
Citation
 López-Rodríguez, ML; Rosado, ML; Benhamú, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Synthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[[4-(o-methoxyphenyl)piperazin-1-yl]methyl]-1, 3-dioxoperhydroimidazo[1,5-alpha]pyridine: a selective 5-HT1A receptor agonist. J Med Chem 39:4439-50 (1996) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50054381
Synonyms:
2-[3-(4-Phenyl-piperazin-1-yl)-propyl]-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione | CHEMBL41978
Type:
Small organic molecule
Emp. Form.:
C20H28N4O2
Mol. Mass.:
356.4619
SMILES:
Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccccc1
Structure:
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