Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50504214
Substrate
n/a
Meas. Tech.
ChEMBL_1814005 (CHEMBL4313579)
Ki
150±n/a nM
Citation
 Mustafa, M; Anwar, S; Elgamal, F; Ahmed, ER; Aly, OM Potent combretastatin A-4 analogs containing 1,2,4-triazole: Synthesis, antiproliferative, anti-tubulin activity, and docking study. Eur J Med Chem 183:0 (2019) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50504214
Synonyms:
CHEMBL4530425
Type:
Small organic molecule
Emp. Form.:
C25H21Cl2FN4O5
Mol. Mass.:
547.362
SMILES:
COc1ccc(cc1Cl)-n1nc(nc1-c1cc(OC)c(OC)c(OC)c1)C(=O)Nc1ccc(F)c(Cl)c1
Structure:
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