Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50504215
Substrate
n/a
Meas. Tech.
ChEMBL_1814005 (CHEMBL4313579)
Ki
260±n/a nM
Citation
 Mustafa, M; Anwar, S; Elgamal, F; Ahmed, ER; Aly, OM Potent combretastatin A-4 analogs containing 1,2,4-triazole: Synthesis, antiproliferative, anti-tubulin activity, and docking study. Eur J Med Chem 183:0 (2019) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50504215
Synonyms:
CHEMBL4463939
Type:
Small organic molecule
Emp. Form.:
C25H22ClFN4O5
Mol. Mass.:
512.917
SMILES:
COc1ccccc1NC(=O)c1nc(-c2cc(OC)c(OC)c(OC)c2)n(n1)-c1ccc(F)c(Cl)c1
Structure:
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