Reaction Details Report a problem with these data
Target
Luteinizing hormone/choriogondaotropin receptor
Ligand
BDBM50505787
Substrate
n/a
Meas. Tech.
ChEMBL_1824038 (CHEMBL4323802)
IC50
78±n/a nM
Citation
Wortmann, L; Lindenthal, B; Muhn, P; Walter, A; Nubbemeyer, R; Heldmann, D; Sobek, L; Morandi, F; Schrey, AK; Moosmayer, D; Günther, J; Kuhnke, J; Koppitz, M; Lücking, U; Röhn, U; Schäfer, M; Nowak-Reppel, K; Kühne, R; Weinmann, H; Langer, G Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent, and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels in Vivo. J Med Chem 62:10321-10341 (2019) [PubMed] Article
More Info.:
Target
Name:
Luteinizing hormone/choriogondaotropin receptor
Synonyms:
Luteinizing hormone/choriogondaotropin receptor
Type:
PROTEIN
Mol. Mass.:
11793.16
Organism:
Macaca fascicularis
Description:
ChEMBL_118864
Residue:
104
Sequence:
FIIICACYIKIYFAVQNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKAPLITVTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFG