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Target
Adenosine receptor A1
Ligand
BDBM50061927
Substrate
n/a
Meas. Tech.
ChEMBL_28838 (CHEMBL649104)
Ki
1200±n/a nM
Citation
 Müller, CE; Geis, U; Hipp, J; Schobert, U; Frobenius, W; Pawlowski, M; Suzuki, F; Sandoval-Ramírez, J Synthesis and structure-activity relationships of 3,7-dimethyl-1-propargylxanthine derivatives, A2A-selective adenosine receptor antagonists. J Med Chem 40:4396-405 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50061927
Synonyms:
8-[(E)-2-(3-Bromo-phenyl)-vinyl]-3,7-dimethyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione | 8-[2-(3-Bromo-phenyl)-vinyl]-3,7-dimethyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione(BS-DMPX) | CHEMBL136047
Type:
Small organic molecule
Emp. Form.:
C18H15BrN4O2
Mol. Mass.:
399.241
SMILES:
Cn1c(\C=C\c2cccc(Br)c2)nc2n(C)c(=O)n(CC#C)c(=O)c12
Structure:
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