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Target
Alpha-synuclein
Ligand
BDBM50510750
Substrate
n/a
Meas. Tech.
ChEMBL_1842065 (CHEMBL4342364)
IC50
1090±n/a nM
Citation
 Liu, H; Chen, L; Zhou, F; Zhang, YX; Xu, J; Xu, M; Bai, SP Anti-oligomerization sheet molecules: Design, synthesis and evaluation of inhibitory activities against ?-synuclein aggregation. Bioorg Med Chem 27:3089-3096 (2019) [PubMed]  Article 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM50510750
Synonyms:
CHEMBL4551721
Type:
Small organic molecule
Emp. Form.:
C16H12N4O2
Mol. Mass.:
292.2921
SMILES:
[O-][N+](=O)c1ccc2[nH]c(\C=C\C=C\c3ccccn3)nc2c1
Structure:
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