Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50510963
Substrate
n/a
Meas. Tech.
ChEMBL_1842739 (CHEMBL4343166)
IC50
250±n/a nM
Citation
 Wan, Y; Li, Y; Yan, C; Yan, M; Tang, Z Indole: A privileged scaffold for the design of anti-cancer agents. Eur J Med Chem 183:0 (2019) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50510963
Synonyms:
D-24851 | Indibulin | ZIO-301
Type:
Small organic molecule
Emp. Form.:
C22H16ClN3O2
Mol. Mass.:
389.834
SMILES:
Clc1ccc(Cn2cc(C(=O)C(=O)Nc3ccncc3)c3ccccc23)cc1
Structure:
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