Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50042209
Substrate
n/a
Meas. Tech.
ChEMBL_1846314 (CHEMBL4346855)
Ki
1940±n/a nM
Citation
 Jiang, J; Seel, CJ; Temirak, A; Namasivayam, V; Arridu, A; Schabikowski, J; Baqi, Y; Hinz, S; Hockemeyer, J; Müller, CE A J Med Chem 62:4032-4055 (2019) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_MOUSE | Adenosine A2b receptor | Adora2b
Type:
PROTEIN
Mol. Mass.:
36130.09
Organism:
Mus musculus
Description:
ChEMBL_11831
Residue:
332
Sequence:
MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHGCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDSATSNCTELGDGIANKSCCPVTCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFMVACKQLQRMELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHKIISRYVLCQAETKGGSGQAGAQSTLSLGL
  
Inhibitor
Name:
BDBM50042209
Synonyms:
4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid | 4-(2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonic acid | CHEMBL8565
Type:
Small organic molecule
Emp. Form.:
C14H14N4O5S
Mol. Mass.:
350.35
SMILES:
CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(cc1)S(O)(=O)=O
Structure:
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