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Target
M-phase inducer phosphatase 1
Ligand
BDBM50068037
Substrate
n/a
Meas. Tech.
ChEMBL_40087 (CHEMBL655756)
IC50
15000±n/a nM
Citation
 Peng, H; Zalkow, LH; Abraham, RT; Powis, G Novel CDC25A phosphatase inhibitors from pyrolysis of 3-alpha-azido-B-homo-6-oxa-4-cholesten-7-one on silica gel. J Med Chem 41:4677-80 (1998) [PubMed]  Article 
Target
Name:
M-phase inducer phosphatase 1
Synonyms:
CDC25A | Dual specificity phosphatase (Cdc25A) | Dual specificity phosphatase Cdc25A | M-phase inducer phosphatase 1 | MPIP1_HUMAN | phosphatase Cdc25
Type:
Protein
Mol. Mass.:
59090.18
Organism:
Homo sapiens (Human)
Description:
P30304
Residue:
524
Sequence:
MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYEQPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAPARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
  
Inhibitor
Name:
BDBM50068037
Synonyms:
5-(Benzoyl-{2-[(2,5-diphenyl-oxazole-4-carbonyl)-amino]-ethyl}-amino)-2-decanoylamino-5-oxo-pentanoic acid | CHEMBL143584
Type:
Small organic molecule
Emp. Form.:
C40H46N4O7
Mol. Mass.:
694.8158
SMILES:
CCCCCCCCCC(=O)NC(CCC(=O)N(CCNC(=O)c1nc(oc1-c1ccccc1)-c1ccccc1)C(=O)c1ccccc1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: