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Target
Thermolysin
Ligand
BDBM50069979
Substrate
n/a
Meas. Tech.
ChEBML_210386
pH
7.2±n/a
Ki
1910000±n/a nM
Comments
extracted
Citation
 Lee, KJ; Kim, DH Inhibition of thermolysin with nitrone-bearing substrate analogs: a new type of thermolysin inhibitors. Bioorg Med Chem Lett 8:323-6 (1999) [PubMed]  Article 
Target
Name:
Thermolysin
Synonyms:
THER_BACTH | npr
Type:
PROTEIN
Mol. Mass.:
60097.54
Organism:
Bacillus thermoproteolyticus
Description:
ChEMBL_1468794
Residue:
548
Sequence:
MKMKMKLASFGLAAGLAAQVFLPYNALASTEHVTWNQQFQTPQFISGDLLKVNGTSPEELVYQYVEKNENKFKFHENAKDTLQLKEKKNDNLGFTFMRFQQTYKGIPVFGAVVTSHVKDGTLTALSGTLIPNLDTKGSLKSGKKLSEKQARDIAEKDLVANVTKEVPEYEQGKDTEFVVYVNGDEASLAYVVNLNFLTPEPGNWLYIIDAVDGKILNKFNQLDAAKPGDVKSITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK
  
Inhibitor
Name:
BDBM50069979
Synonyms:
CHEMBL110107 | methyl 2-[(Z)-benzylidene(oxido)amino]-3-phenylpropanoate
Type:
Small organic molecule
Emp. Form.:
C17H17NO3
Mol. Mass.:
283.3218
SMILES:
COC(=O)C(Cc1ccccc1)[N+](\[O-])=C\c1ccccc1
Structure:
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