Reaction Details Report a problem with these data
Target
P2Y purinoceptor 14
Ligand
BDBM50515479
Substrate
n/a
Meas. Tech.
ChEMBL_1861162 (CHEMBL4362018)
IC50
5.1±n/a nM
Citation
 Zhang, Z; Hao, K; Li, H; Lu, R; Liu, C; Zhou, M; Li, B; Meng, Z; Hu, Q; Jiang, C Design, synthesis and anti-inflammatory evaluation of 3-amide benzoic acid derivatives as novel P2Y Eur J Med Chem 181:0 (2019) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 14
Synonyms:
GPR105 | Insulin Receptor-Related Protein (INSRR) | KIAA0001 | P2RY14 | P2Y14_HUMAN | Purinergic receptor P2Y14
Type:
PROTEIN
Mol. Mass.:
38991.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1502487
Residue:
338
Sequence:
MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
  
Inhibitor
Name:
BDBM50515479
Synonyms:
CHEMBL4526840
Type:
Small organic molecule
Emp. Form.:
C25H23N3O5
Mol. Mass.:
445.4672
SMILES:
OC(=O)c1cc(NC(=O)c2ccc(cc2)[N+]([O-])=O)cc(c1)-c1ccc(cc1)C1CCNCC1
Structure:
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