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Target
Chymotrypsin-C
Ligand
BDBM50070595
Substrate
n/a
Meas. Tech.
ChEBML_197807
Ki
80000±n/a nM
Citation
 Lu, T; Tomczuk, B; Illig, CR; Bone, R; Murphy, L; Spurlino, J; Salemme, FR; Soll, RM In vitro evaluation and crystallographic analysis of a new class of selective, non-amide-based thrombin inhibitors. Bioorg Med Chem Lett 8:1595-600 (1999) [PubMed]  Article 
Target
Name:
Chymotrypsin-C
Synonyms:
CLCR | CTRC | CTRC_HUMAN | Caldecrin | Chymotrypsin | Chymotrypsin C | Chymotrypsin-C
Type:
Enzyme
Mol. Mass.:
29487.98
Organism:
Homo sapiens (Human)
Description:
Q99895
Residue:
268
Sequence:
MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
  
Inhibitor
Name:
BDBM50070595
Synonyms:
2-Chloro-benzenesulfonic acid 3-(5-guanidino-pentyloxy)-5-methyl-phenyl ester | CHEMBL287910
Type:
Small organic molecule
Emp. Form.:
C19H24ClN3O4S
Mol. Mass.:
425.93
SMILES:
Cc1cc(OCCCCCNC(N)=N)cc(OS(=O)(=O)c2ccccc2Cl)c1
Structure:
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