Target
Cereblon isoform 4
Ligand
BDBM50516590
Substrate
n/a
Meas. Tech.
ChEMBL_1866003 (CHEMBL4366978)
Ki
>40000±n/a nM
Citation
 Heim, CPliatsika, DMousavizadeh, FBär, KHernandez Alvarez, BGiannis, AHartmann, MD De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives. J Med Chem 62:6615-6629 (2019) [PubMed]  Article 
Target
Name:
Cereblon isoform 4
Synonyms:
Cereblon isoform 4
Type:
PROTEIN
Mol. Mass.:
13620.40
Organism:
Magnetospirillum gryphiswaldense
Description:
ChEMBL_116733
Residue:
124
Sequence:
MPLDAGGQNSTQMVLAPGASIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQGLRLIGAPSGEFSWFKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIKDRLAEGPAD
  
Inhibitor
Name:
BDBM50516590
Synonyms:
CHEMBL4581801
Type:
Small organic molecule
Emp. Form.:
C12H12N2O3
Mol. Mass.:
232.2353
SMILES:
O=C(Cc1ccccc1)NC1CC(=O)NC1=O
Structure:
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