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Target
Proteasome subunit beta type-5
Ligand
BDBM50516759
Substrate
n/a
Meas. Tech.
ChEMBL_1866705 (CHEMBL4367680)
Ki
17±n/a nM
Citation
 Fernandes, GFS; Denny, WA; Dos Santos, JL Boron in drug design: Recent advances in the development of new therapeutic agents. Eur J Med Chem 179:791-804 (2019) [PubMed]  Article 
Target
Name:
Proteasome subunit beta type-5
Synonyms:
20S proteasome chymotrypsin-like | 26S proteosome | LMPX | MB1 | PSB5_HUMAN | PSMB5 | Proteasome Macropain subunit MB1 | Proteasome subunit beta type-1/beta type-5 | X
Type:
Protein
Mol. Mass.:
28480.96
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
263
Sequence:
MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP
  
Inhibitor
Name:
BDBM50516759
Synonyms:
CHEMBL4458610
Type:
Small organic molecule
Emp. Form.:
C21H30BN3O4
Mol. Mass.:
399.292
SMILES:
CCc1cccc(Nc2ccn(CCC(=O)N[C@@H](CC(C)C)B(O)O)c(=O)c2)c1 |r|
Structure:
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