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Target
Beta-lactamase TEM
Ligand
BDBM50516761
Substrate
n/a
Meas. Tech.
ChEMBL_1866660 (CHEMBL4367635)
Ki
40±n/a nM
Citation
 Fernandes, GFS; Denny, WA; Dos Santos, JL Boron in drug design: Recent advances in the development of new therapeutic agents. Eur J Med Chem 179:791-804 (2019) [PubMed]  Article 
Target
Name:
Beta-lactamase TEM
Synonyms:
BLAT_ECOLX | Bacterial beta-lactamase TEM | Beta-lactamase (TEM-1) | Beta-lactamase TEM | Beta-lactamase TEM-1 | Beta-lactamase TEM-1b | Beta-lactamase TEM1D | Beta-lactamase TEM1E | Beta-lactamase TEM1F | TEM beta lactamase | TEM extended-spectrum beta-lactamase | TEM-1 beta-lactamase | bla
Type:
Enzyme
Mol. Mass.:
31512.33
Organism:
Escherichia coli
Description:
P62593
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM50516761
Synonyms:
CHEMBL3286879
Type:
Small organic molecule
Emp. Form.:
C11H9BO4S
Mol. Mass.:
248.063
SMILES:
OB(O)c1sc2ccccc2c1\C=C\C(O)=O
Structure:
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