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Target
D(4) dopamine receptor
Ligand
BDBM50077000
Substrate
n/a
Meas. Tech.
ChEBML_63105
Ki
140±n/a nM
Citation
 Moore, KW; Bonner, K; Jones, EA; Emms, F; Leeson, PD; Marwood, R; Patel, S; Patel, S; Rowley, M; Thomas, S; Carling, RW 4-N-linked-heterocyclic piperidine derivatives with high affinity and selectivity for human dopamine D4 receptors. Bioorg Med Chem Lett 9:1285-90 (1999) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50077000
Synonyms:
1-Benzyl-4-(3-methyl-5-phenyl-pyrazol-1-yl)-piperidine | CHEMBL24809
Type:
Small organic molecule
Emp. Form.:
C22H25N3
Mol. Mass.:
331.454
SMILES:
Cc1cc(-c2ccccc2)n(n1)C1CCN(Cc2ccccc2)CC1
Structure:
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