Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50017975
Substrate
n/a
Meas. Tech.
ChEMBL_1888982 (CHEMBL4390736)
Ki
631±n/a nM
Citation
 Al-Ghanim, L; Zhu, XY; Asong, G; Ablordeppey, SY SYA 013 analogs as moderately selective sigma-2 (? Bioorg Med Chem 27:2421-2426 (2019) [PubMed]  Article 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM50017975
Synonyms:
CHEMBL3289383
Type:
Small organic molecule
Emp. Form.:
C19H22ClFN2OS
Mol. Mass.:
380.907
SMILES:
[O-][S+](CCCN1CCN(CC1)c1ccc(Cl)cc1)c1ccc(F)cc1
Structure:
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