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Target
Fatty acid-binding protein, adipocyte
Ligand
BDBM50468371
Substrate
n/a
Meas. Tech.
ChEMBL_1897608 (CHEMBL4399643)
IC50
1690±n/a nM
Citation
 He, Y; Dou, H; Gao, D; Wang, T; Zhang, M; Wang, H; Li, Y Identification of new dual FABP4/5 inhibitors based on a naphthalene-1-sulfonamide FABP4 inhibitor. Bioorg Med Chem 27:0 (2019) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, adipocyte
Synonyms:
A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4)
Type:
Enzyme
Mol. Mass.:
14719.23
Organism:
Homo sapiens (Human)
Description:
P15090
Residue:
132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
  
Inhibitor
Name:
BDBM50468371
Synonyms:
CHEMBL4283424
Type:
Small organic molecule
Emp. Form.:
C18H14FNO5S
Mol. Mass.:
375.371
SMILES:
COc1ccc(c2ccccc12)S(=O)(=O)Nc1ccc(F)c(c1)C(O)=O
Structure:
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