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Target
Free fatty acid receptor 3
Ligand
BDBM50527502
Substrate
n/a
Meas. Tech.
ChEMBL_1902642 (CHEMBL4404864)
EC50
692±n/a nM
Citation
 Ulven, ER; Quon, T; Sergeev, E; Barki, N; Brvar, M; Hudson, BD; Dutta, P; Hansen, AH; Bielefeldt, LŲ; Tobin, AB; McKenzie, CJ; Milligan, G; Ulven, T Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators. J Med Chem 63:3577-3595 (2020) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 3
Synonyms:
FFAR3 | FFAR3_HUMAN | GPR41
Type:
PROTEIN
Mol. Mass.:
38655.15
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508992
Residue:
346
Sequence:
MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES
  
Inhibitor
Name:
BDBM50527502
Synonyms:
CHEMBL4515057
Type:
Small organic molecule
Emp. Form.:
C21H28N2O3
Mol. Mass.:
356.4586
SMILES:
COC(=O)C1=C(C)NC(C)=C(C1CC(C)C)C(=O)Nc1ccccc1C |c:4,9|
Structure:
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