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Target
Cell division cycle protein 20 homolog
Ligand
BDBM50527906
Substrate
n/a
Meas. Tech.
ChEMBL_1903906 (CHEMBL4406128)
Kd
123000±n/a nM
Citation
 Huang, P; Le, X; Huang, F; Yang, J; Yang, H; Ma, J; Hu, G; Li, Q; Chen, Z Discovery of a Dual Tubulin Polymerization and Cell Division Cycle 20 Homologue Inhibitor via Structural Modification on Apcin. J Med Chem 63:4685-4700 (2020) [PubMed]  Article 
Target
Name:
Cell division cycle protein 20 homolog
Synonyms:
CDC20 | CDC20_HUMAN | Cell division cycle protein 20 homolog | p55CDC
Type:
PROTEIN
Mol. Mass.:
54744.11
Organism:
Homo sapiens
Description:
ChEMBL_119033
Residue:
499
Sequence:
MAQFAFESDLHSLLQLDAPIPNAPPARWQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQMEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFDVEEAKILRLSGKPQNAPEGYQNRLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQGIR
  
Inhibitor
Name:
BDBM50527906
Synonyms:
CHEMBL4455572
Type:
Small organic molecule
Emp. Form.:
C13H14Cl3N7O4
Mol. Mass.:
438.654
SMILES:
Cc1ncc(n1CCOC(=O)NC(Nc1ncccn1)C(Cl)(Cl)Cl)[N+]([O-])=O
Structure:
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