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Target
Trypsin
Ligand
BDBM50085342
Substrate
n/a
Meas. Tech.
ChEBML_213023
IC50
>1000000±n/a nM
Citation
 Hayashi, Y; Iijima, K; Katada, J; Kiso, Y Structure-activity relationship studies of chloromethyl ketone derivatives for selective human chymase inhibitors. Bioorg Med Chem Lett 10:199-201 (2000) [PubMed]  Article 
Target
Name:
Trypsin
Synonyms:
TRYP_PIG
Type:
PROTEIN
Mol. Mass.:
24411.24
Organism:
Sus scrofa
Description:
ChEMBL_1450738
Residue:
231
Sequence:
FPTDDDDKIVGGYTCAANSIPYQVSLNSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN
  
Inhibitor
Name:
BDBM50085342
Synonyms:
CHEMBL61059 | N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(2,3-dimethoxy-phenyl)-propionamide
Type:
Small organic molecule
Emp. Form.:
C21H24ClNO4
Mol. Mass.:
389.873
SMILES:
COc1cccc(CCC(=O)N[C@@H](Cc2ccccc2)C(=O)CCl)c1OC
Structure:
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