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Target
Adenosine receptor A2a
Ligand
BDBM50086132
Substrate
n/a
Meas. Tech.
ChEMBL_31053 (CHEMBL642124)
Ki
66±n/a nM
Citation
 Colotta, V; Catarzi, D; Varano, F; Cecchi, L; Filacchioni, G; Martini, C; Trincavelli, L; Lucacchini, A 1,2,4-Triazolo[4,3-a]quinoxalin-1-one: a versatile tool for the synthesis of potent and selective adenosine receptor antagonists. J Med Chem 43:1158-64 (2000) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50086132
Synonyms:
4-(cyclohexylamino)-2-(3-fluorophenyl)-[1,2,4]triazolo[4,3-a]quinoxalin-1(2H)-one | 4-Cyclohexylamino-2-(3-fluoro-phenyl)-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one | CHEMBL279870
Type:
Small organic molecule
Emp. Form.:
C21H20FN5O
Mol. Mass.:
377.4148
SMILES:
Fc1cccc(c1)-n1nc2c(NC3CCCCC3)nc3ccccc3n2c1=O
Structure:
Search PDB for entries with ligand similarity: