Target
Delta-type opioid receptor
Ligand
BDBM50086357
Substrate
n/a
Meas. Tech.
ChEBML_145496
Ki
>10000±n/a nM
Citation
 Allen, MPBlake, JFBryce, DKHaggan, MELiras, SMcLean, SSegelstein, BE Design, synthesis and biological evaluation of 3-amino-3-phenylpropionamide derivatives as novel mu opioid receptor ligands. Bioorg Med Chem Lett 10:523-6 (2000) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50086357
Synonyms:
2,2-Dimethyl-3-methylamino-N-phenethyl-3-phenyl-propionamide | CHEMBL146918
Type:
Small organic molecule
Emp. Form.:
C20H26N2O
Mol. Mass.:
310.4332
SMILES:
CNC(c1ccccc1)C(C)(C)C(=O)NCCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: