Reaction Details Report a problem with these data
Target
Interleukin-2
Ligand
BDBM50532281
Substrate
n/a
Meas. Tech.
ChEMBL_1922393 (CHEMBL4425349)
Kd
4200±n/a nM
Citation
 Franzini, RM; Randolph, C Chemical Space of DNA-Encoded Libraries. J Med Chem 59:6629-44 (2016) [PubMed]  Article 
Target
Name:
Interleukin-2
Synonyms:
IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:
Enzyme
Mol. Mass.:
17630.05
Organism:
Homo sapiens (Human)
Description:
P60568
Residue:
153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
  
Inhibitor
Name:
BDBM50532281
Synonyms:
CHEMBL4515387
Type:
Small organic molecule
Emp. Form.:
C26H28N2O3
Mol. Mass.:
416.5121
SMILES:
CCCC#Cc1ccc(C[C@@H](NC(=O)CCn2c(C)cc3ccccc23)C(O)=O)cc1 |r|
Structure:
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