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Target
Delta-type opioid receptor
Ligand
BDBM50088739
Substrate
n/a
Meas. Tech.
ChEBML_147034
Ki
93±n/a nM
Citation
 Boyd, RE; Carson, JR; Codd, EE; Gauthier, AD; Neilson, LA; Zhang, SP Synthesis and binding affinities of 4-diarylaminotropanes, a new class of delta opioid agonists. Bioorg Med Chem Lett 10:1109-11 (2000) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40465.04
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor.
Residue:
372
Sequence:
MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50088739
Synonyms:
CHEMBL13360 | {4-[((1R,3S,5S)-8-Phenethyl-8-aza-bicyclo[3.2.1]oct-3-yl)-phenyl-amino]-phenyl}-pyrrolidin-1-yl-methanone
Type:
Small organic molecule
Emp. Form.:
C32H37N3O
Mol. Mass.:
479.6557
SMILES:
O=C(N1CCCC1)c1ccc(cc1)N([C@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccccc1)c1ccccc1 |THB:22:21:14.20.15:17.18|
Structure:
Search PDB for entries with ligand similarity: