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Target
Delta-type opioid receptor
Ligand
BDBM50088749
Substrate
n/a
Meas. Tech.
ChEBML_147034
Ki
3±n/a nM
Citation
 Boyd, RE; Carson, JR; Codd, EE; Gauthier, AD; Neilson, LA; Zhang, SP Synthesis and binding affinities of 4-diarylaminotropanes, a new class of delta opioid agonists. Bioorg Med Chem Lett 10:1109-11 (2000) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40465.04
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor.
Residue:
372
Sequence:
MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50088749
Synonyms:
CHEMBL13286 | N,N-Diethyl-4-[phenyl-((1R,3S,5S)-8-propyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amino]-benzamide
Type:
Small organic molecule
Emp. Form.:
C27H37N3O
Mol. Mass.:
419.6022
SMILES:
CCCN1[C@H]2CC[C@@H]1C[C@H](C2)N(c1ccccc1)c1ccc(cc1)C(=O)N(CC)CC |THB:2:3:9.8.10:6.5|
Structure:
Search PDB for entries with ligand similarity: