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Target
Delta-type opioid receptor
Ligand
BDBM50088724
Substrate
n/a
Meas. Tech.
ChEBML_147034
Ki
12±n/a nM
Citation
 Boyd, RE; Carson, JR; Codd, EE; Gauthier, AD; Neilson, LA; Zhang, SP Synthesis and binding affinities of 4-diarylaminotropanes, a new class of delta opioid agonists. Bioorg Med Chem Lett 10:1109-11 (2000) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40465.04
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor.
Residue:
372
Sequence:
MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50088724
Synonyms:
CHEMBL275011 | N,N-Diethyl-4-{[(1R,3R,5S)-8-(3-methyl-but-2-enyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-phenyl-amino}-benzamide
Type:
Small organic molecule
Emp. Form.:
C29H39N3O
Mol. Mass.:
445.6395
SMILES:
[#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#7](-[#6@@H]-1-[#6]-[#6@@H]-2-[#6]-[#6]-[#6@H](-[#6]-1)-[#7]-2-[#6]\[#6]=[#6](\[#6])-[#6])-c1ccccc1 |THB:22:21:14.20.15:17.18|
Structure:
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