Reaction Details Report a problem with these data
Target
Fatty acid-binding protein 5
Ligand
BDBM50538236
Substrate
n/a
Meas. Tech.
ChEMBL_1972441 (CHEMBL4605259)
Ki
430±n/a nM
Citation
 Su, H; Zou, Y; Chen, G; Dou, H; Xie, H; Yuan, X; Zhang, X; Zhang, N; Li, M; Xu, Y Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J Med Chem 63:4090-4106 (2020) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein 5
Synonyms:
FABP5 | FABP5_HUMAN | Fatty acid binding protein epidermal | Fatty acid-binding protein 5 (FABP5)
Type:
Enzyme
Mol. Mass.:
15164.79
Organism:
Homo sapiens (Human)
Description:
Q01469
Residue:
135
Sequence:
MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTLKTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVECVMNNVTCTRIYEKVE
  
Inhibitor
Name:
BDBM50538236
Synonyms:
CHEMBL4644782
Type:
Small organic molecule
Emp. Form.:
C21H14ClNO3
Mol. Mass.:
363.794
SMILES:
OC(=O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2occc2c1
Structure:
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