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Target
Glucose-dependent insulinotropic receptor
Ligand
BDBM50540315
Substrate
n/a
Meas. Tech.
ChEMBL_1981607 (CHEMBL4614869)
EC50
1.7±n/a nM
Citation
 Cerny, MA; Kalgutkar, AS; Obach, RS; Sharma, R; Spracklin, DK; Walker, GS Effective Application of Metabolite Profiling in Drug Design and Discovery. J Med Chem 63:6387-6406 (2020) [PubMed]  Article 
Target
Name:
Glucose-dependent insulinotropic receptor
Synonyms:
G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor
Type:
Protein
Mol. Mass.:
36901.49
Organism:
Homo sapiens (Human)
Description:
Q8TDV5
Residue:
335
Sequence:
MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
  
Inhibitor
Name:
BDBM50540315
Synonyms:
CHEMBL4639701
Type:
Small organic molecule
Emp. Form.:
C24H24N6O
Mol. Mass.:
412.487
SMILES:
CC(C)c1noc(n1)C1CCN(CC1)c1ccc(cn1)-c1cc(C)c(cc1C#N)C#N
Structure:
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