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Target
D(2) dopamine receptor
Ligand
BDBM50099788
Substrate
n/a
Meas. Tech.
ChEMBL_61588 (CHEMBL675760)
IC50
21900±n/a nM
Citation
 Cabedo, N; Andreu, I; Ramírez De Arellano, MC; Chagraoui, A; Serrano, A; Bermejo, A; Protais, P; Cortes, D Enantioselective syntheses of dopaminergic (R)- and (S)-benzyltetrahydroisoquinolines. J Med Chem 44:1794-801 (2001) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50099788
Synonyms:
5-Benzyl-6-propyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline | CHEMBL53520
Type:
Small organic molecule
Emp. Form.:
C20H23NO2
Mol. Mass.:
309.4021
SMILES:
CCCN1CCc2cc3OCOc3cc2[C@@H]1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: